Population data on the X chromosome short tandem repeat loci DXS10011, DXS101, DXS6789, DXS7132, DXS8377, and DXS9895 in Taiwan.

نویسندگان

  • Meng-Yi Chen
  • Chang-En Pu
چکیده

X chromosome linked short tandem repeat (STR) are powerful auxiliary systems to genomic STR, they are helpful for differentiating if two women have the same father directly, avoiding some of the ambiguity generated from sibship estimation. This report contains the results of population studies on the X chromosome STR DXS10011, DXS101, DXS6789, DXS7132, DXS8377 and DXS9895 carried out in Taiwan. The common alleles of each locus were sequenced and used in a control ladder to type unknown samples. The numbers of unrelated individuals were 273 (female 92 and male 181) for DXS10011 locus, 448 (female 135 and male 313) for DXS101 locus, 447 (female 135 and male 312) for DXS6789 locus, 414 (female 119 and male 295) for DXS7132 locus, 450 (female 135 and male 315) for DXS8377 locus and 413 (female 120 and male 293) for DXS9895 locus. These STR polymorphisms will be a useful marker for parentage testing especially when disputed blood relative is female.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Genetic Polymorphisms of Nine X-STR Loci in Four Population Groups from Inner Mongolia, China

Nine short tandem repeat (STR) markers on the X chromosome (DXS101, DXS6789, DXS6799, DXS6804, DXS7132, DXS7133, DXS7423, DXS8378, and HPRTB) were analyzed in four population groups (Mongol, Ewenki, Oroqen, and Daur) from Inner Mongolia, China, in order to learn about the genetic diversity, forensic suitability, and possible genetic affinities of the populations. Frequency estimates, Hardy-Wein...

متن کامل

Allele and Haplotype Diversity of 26 X-STR Loci in Four Nationality Populations from China

BACKGROUND Haplotype analysis of closely associated markers has proven to be a powerful tool in kinship analysis, especially when short tandem repeats (STR) fail to resolve uncertainty in relationship analysis. STR located on the X chromosome show stronger linkage disequilibrium compared with autosomal STR. So, it is necessary to estimate the haplotype frequencies directly from population studi...

متن کامل

Genetic Variation of Informative Short Tandem Repeat (STR) Loci in an Iranian Population

In the present study, genotyping of six short tandem repeat (STR) loci including CSF1PO, D16S539, F13A01, F13B, LPL and HPRTB was performed on genomic DNA from 127 unrelated individuals from the Iranian province of Isfahan. The results indicated that the allele and genotype distributions were in accordance with Hardy-Weinberg expectations. The observed heterozygosity (Ho), expected heterozygosi...

متن کامل

Application of microsatellite loci on the chromosome X for rapid prenatal detection of the chromosome X numerical abnormalities

AIM To determine the value of short-tandem repeat markers on the chromosome X (X-STR) for prenatal diagnostics of the chromosome X numerical disorders. METHODS We investigated the genetic variability of 5 X-markers (DXS9895, DXS6810, DXS6803, GATA172D05, and HPRTB) in 183 healthy Croatian individuals (90 men and 93 women). We also tested 13 patients with X chromosome disorders (Turner syndrom...

متن کامل

Genetic analysis of 19 X chromosome STR loci for forensic purposes in four Chinese ethnic groups

A new 19 X- short tandem repeat (STR) multiplex PCR system has recently been developed, though its applicability in forensic studies has not been thoroughly assessed. In this study, 932 unrelated individuals from four Chinese ethnic groups (Han, Tibet, Uighur and Hui) were successfully genotyped using this new multiplex PCR system. Our results showed significant linkage disequilibrium between m...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Forensic science international

دوره 146 1  شماره 

صفحات  -

تاریخ انتشار 2004